Apicomplexan Energy Metabolism: Carbon Source Promiscuity and the Quiescence Hyperbole
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چکیده
منابع مشابه
Apicomplexan Energy Metabolism: Carbon Source Promiscuity and the Quiescence Hyperbole.
The nature of energy metabolism in apicomplexan parasites has been closely investigated in the recent years. Studies in Plasmodium spp. and Toxoplasma gondii in particular have revealed that these parasites are able to employ enzymes in non-traditional ways, while utilizing multiple anaplerotic routes into a canonical tricarboxylic acid (TCA) cycle to satisfy their energy requirements. Importan...
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Metabolic pathways are often considered "perfected" or at least predictable as substrates efficiently rearrange into products through the intervention of an optimized enzyme. Moreover, single catalytic steps link up, forming a myriad of metabolic circuits that are often modeled with a high degree of certainty. However, on closer examination, most enzymes are not precise with respect to their ac...
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ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2016
ISSN: 1471-4922
DOI: 10.1016/j.pt.2015.09.001